Not all lesions require surgical resection, and in general cysts do not require surgical resection, only in isolated cases, such as: cystic lesions as thick-walled cysts, neoplastic organisms found in cysts, intracapsular fluid found to be bloody by puncture, and heterogeneous cells found in puncture fluid by cytological examination require surgical treatment. Solid nodules or tumors that require surgical excision have two factors: 1. Treatment factors: surgical excision is required for treatment, because such lesions cannot be cured by taking medication or injections (drugs). 2. Confirmation factor: The global gold standard for solid tumor diagnosis is histopathological diagnosis, so the result of pathology is very important, and even good imaging examination is not the basis for confirmation of diagnosis and cannot replace pathological examination. The imaging examinations such as ultrasound, mammography, CT, etc. are indirect examinations, while the pathological examination is to confirm the diagnosis of the lesion by staining the tissues and cells and visually observing the changes of the cells and tissues with microscope. For lesions of unclear nature, surgery or puncture biopsy should be performed to confirm the diagnosis. Clearly palpable masses, i.e., solid masses with a hard texture that can be “felt,” are generally (except in some cases of suspected chronic inflammatory granulomas) subjected to surgery and pathological confirmation. Some non-palpable breast lesions (NPBL Non-Palpable Breast Lesions) of unknown nature: i.e., “non-palpable masses”, also require surgical biopsy for pathological confirmation.