Double lower limb arterial intima-media thickening becomes small plaque, mainly because of the three high factors and bad dietary habits and other causes. This situation is not particularly serious, can be under the guidance of the doctor, appropriate oral medication. 1. Lowering blood lipids: high blood lipid levels can cause the formation of small plaques in the arteries, medication for cholesterol-lowering drugs, such as simvastatin, lovastatin, etc., to lower triglyceride drugs, such as fenofibrate. 2. Lowering blood pressure: High blood pressure can cause thickening of the arterial lining and the formation of small plaques. The main treatment is to control the blood pressure at the normal level, and the doctor will choose the appropriate antihypertensive drugs according to the patient’s condition, such as Enalapril, Chlorthalidomide, Nifedipine, Propranolol and so on. 3. Lowering blood sugar: High blood sugar can also lead to the formation of plaque in the arteries, and the treatment is based on lowering blood sugar. Drugs include metformin or insulin injection. 4. Correct daily dietary habits: Diet should limit the intake of cholesterol and fatty acids, focus on light and easy to digest, low oil and low salt, quit smoking, moderate exercise, and weight control. If the above symptoms occur, please go to the hospital in time for consultation and treatment, and do not use medication privately, which may cause danger.