A short and mild toothache will not cause an increase in blood pressure, but if it is a persistent or severe toothache, it will cause an increase in blood pressure. There are many causes of toothache, tooth and periodontal tissue lesions are the main cause of toothache, usually inflammatory diseases, such as dental caries, periodontitis, pulpitis, dental trauma, acute periapical inflammation, alveolar abscess, periodontal abscess, and acute suppurative maxillary sinusitis, acute suppurative jaw bone pulpitis, acute suppurative otitis media, etc. When tooth pain is present, the organism is in a stressful state of tension and anxiety, which affects eating and resting, plus the stimulation of pain itself, which increases sympathetic excitability, accelerates heart rate, increases cardiac output, increases peripheral vasoconstriction and raises blood pressure. The elevation of blood pressure caused by toothache is transient, but for hypertensive patients, transient elevation of blood pressure can also pose a great risk. Therefore, hypertensive patients should pay attention to oral hygiene, actively control blood pressure, and treat oral diseases as soon as they appear.