What medication is best for swollen feet and neck depends on what is causing it. Most edema can be relieved by oral diuretics, such as oral furosemide or spironolactone. For kidney disease, especially nephrotic syndrome patients, there can be hypoproteinemia, edema, a large amount of proteinuria, such a situation strictly refused simple diuretic treatment. Treatment with oral furosemide and spironolactone alone can lead to the risk of thrombosis, so it is recommended to identify the cause of the disease. In this case, intravenous infusion of human albumin can be followed by dilatation, and then apply diuretic therapy, either oral furosemide, spironolactone, or intravenous infusion of traceramide, or oral tolvaptan and other medications, usually with good results. If the edema is difficult to eliminate, it is recommended to further investigate the thyroid function, whether it is combined with hyperthyroidism or hypothyroidism, and actively supplement the corresponding hormone therapy.