With the aging of society becoming more and more serious, the prevalence of some diseases related to aging is also rising year by year, such as Parkinson’s disease and Alzheimer’s disease. During consultation, patients often ask Prof. Wang Xuelian if Parkinson’s disease is Alzheimer’s disease. Patients with Parkinson’s disease have dull facial expressions, move stiffly and slowly, and seem to react half a beat slower, all of which can easily make people suspect that they have Alzheimer’s. Is Parkinson’s disease the same thing? So are they the same thing or not? And what is the relationship between them? These are two completely different diseases. Although the problem with both diseases is in the “mind”, Parkinson’s disease is caused by lesions in the dopamine nerve cells in the substantia nigra of the brain, while Alzheimer’s disease is caused by lesions in the hippocampus of the temporal lobe of the brain. Parkinson’s disease, also known as “jittery disease”, is a neurodegenerative disease that mainly affects motor function, but the patient’s intelligence is not affected. Parkinson’s disease does not directly shorten a person’s life expectancy, but it can cause a person to lose the ability to work and live. Moreover, the early stage of Parkinson’s disease progresses rapidly, and the first 3-5 years of its onset is the best time for drug treatment. At this time, the treatment cost is small and the effect is good, and the patient’s disease progression can be effectively slowed down for 15-20 years, and can even live like a normal person. However, early symptoms of Parkinson’s disease are often atypical and easily overlooked or misdiagnosed. Some people are diagnosed with cervical spondylosis because of neck pain, others are diagnosed with lumbar spondylosis because of back pain, and still others are misdiagnosed with stroke because they shuffle when walking. Alzheimer’s disease, by which people generally refer to Alzheimer’s disease, is a neurodegenerative disease that primarily involves the intellect, while motor function is not affected. Symptoms include progressive cognitive decline, such as poorer memory (e.g., forgetting what you said before and then forgetting it later, often not being able to find things), poor concentration, reduced executive function (things you used to be able to do well are now not done well or can’t be done), reduced visuospatial function (e.g., starting to lose your way), and impaired language (e.g., not being able to name common objects, often not being able to use words well enough), among other things. It is important to note that some anti-Parkinsonian medications may also cause cognitive decline or mental behavioral abnormalities. For example, Antan (phenelzine hydrochloride), a central anticholinergic drug commonly used in the clinic, is very effective in controlling tremor symptoms in patients with PD, but it can also lead to side effects such as somnolence, depression, and memory loss, and amantadine, dopamine agonists, and monoamine oxidase-B inhibitors are also at risk for hallucinations, all of which can lead to pharmacological dementia. All of these have the potential to cause pharmacologic dementia. Therefore, the use of medication in Parkinson’s disease places particular emphasis on individualization, and some drugs should be used with caution in patients at high risk of developing Parkinson’s dementia, with the principle of medication use emphasizing optimal efficacy at the lowest possible dose. Once a Parkinson’s patient develops suspected dementia symptoms, he or she should seek immediate medical attention and be identified by a medical professional. Parkinson’s (Tremor Paralysis) Disease Currently, Parkinson’s (Tremor Paralysis) Disease can be treated with medication and surgery. In terms of medication, levodopa preparation is the main treatment drug, which can effectively relieve the symptoms. In terms of surgery, brain pacemaker surgery can relieve Parkinson’s disease (tremor paralysis, rigidity). Different Parkinson’s patients find the suitable treatment plan according to their own situation.