Contact dermatitis is an acute or chronic inflammatory reaction that occurs at the site of skin-mucosal contact due to exposure to certain exogenous substances. Depending on the pathogenesis, the etiology can be divided into primary irritants and contact sensitizers. The treatment of contact dermatitis is divided into systemic medication and topical medication. 1. Systemic medication: Depending on the severity of the disease, antihistamines or glucocorticoids can be taken internally. Prednisone 20mg twice a day can be used to treat severe, generalized inflammation, after a short course of treatment generally do not need to gradually reduce the amount (under the guidance of a doctor to take). 2, topical medication: can be treated according to the treatment of acute, subacute and chronic dermatitis. In the acute stage, the redness and swelling is obvious, then the topical application of glycolite lotion, exudate more with 3% boric acid solution cold wet compress, each 15-30 minutes, several times a day, for 1 to 3 days, until the control of exudation. In the subacute stage, glucocorticoid paste or zinc oxide oil is used topically when there is a small amount of exudation, and glucocorticoid cream is used when there is no exudate. Topical antibiotics are added when there is infection. In the chronic phase, ointments with anti-inflammatory effects are generally used. The actual diaper dermatitis should be changed at any time, keep the pubic area and buttocks clean and dry, use less soap to avoid aggravating the irritation, and topical zinc oxide oil can be used locally. The treatment of contact dermatitis is to find the cause, quickly remove the contact and actively symptomatic treatment. After the hypersensitivity contact dermatitis is cured, you should try to avoid contact with the allergen again to avoid recurrence.