Itchy skin with herpes could be shingles, sweat blisters, etc. It can be treated with topical or oral medication. 1. Herpes zoster: herpes zoster is caused by varicella zoster virus infection, itching, pain and other symptoms, can be prescribed oral antiviral drugs such as acyclovir, vasiclovir treatment, local topical acyclovir ointment and so on. 2. Sweat herpes: sweat herpes mainly occurs on the hands and feet, manifested in the palm and plantar areas of the multiple pinpoint-sized blisters, can be used externally with glucocorticoid drugs such as halomethasone ointment, flumethasone ointment and other medications, itching is obvious that can be combined with oral chlordiazepoxide, avastin and so on. Herpes itchy skin to target the cause of the disease, symptomatic treatment, the above drugs should be used in accordance with medical advice.