Tonsil suppuration infection in children can be controlled with anti-infective drugs such as penicillin and cefdinir depending on the type of infection. Tonsil suppuration infection is mostly secondary to tonsillitis, mainly caused by hemolytic streptococcus, influenza bacillus, non-hemolytic streptococcus, pneumococcus, staphylococcus, etc. in the oral cavity and tonsils. For those who have clear symptoms of bacterial infection such as tonsil suppuration and generalized fever, medication is needed for anti-infective treatment. For common bacterial infections, commonly used antibacterial drugs include penicillin, cefuroxime, cefdinir, metronidazole and other drugs, but it should be noted that for children, avoid the use of levofloxacin and other quinolone antibiotics. Tonsillar suppuration needs to be differentiated from diseases such as tonsillar keratosis and diphtheria. It is recommended to go to the hospital when the above mentioned signs of suppurative infections occur.