The causes of parenchymal lung nodules include tumors, Mycobacterium tuberculosis infection, fungal infection, etc., which need to be treated medically or surgically depending on the cause. 1. Tumor: For benign or malignant tumors, TV-assisted thoracoscopic surgery or open thoracotomy can be considered for resection according to the specific situation. 2. Mycobacterium tuberculosis infection: for mycobacterium tuberculosis infection, oral isoniazid, rifampicin and so on can be taken as prescribed by the doctor, which can kill mycobacterium tuberculosis and achieve the purpose of controlling the condition. 3. Fungal infections: for fungal infections, oral itraconazole, fluconazole and other antifungal drugs can be prescribed to control the infection. It is recommended that people with substantial pulmonary nodules go to regular hospitals in time to clarify the cause of the disease, and if treatment is needed, it should be standardized under the guidance of a doctor.