The initial symptom may be a sore throat, but since this symptom is not specific, it is not possible to determine whether there is a new crown infection from this symptom. New coronavirus infection shows diversity, sore throat is not a typical manifestation, new crown pneumonia in the early stage of the main clinical manifestations of fever, usually around 37 ℃, accompanied by nasal congestion, runny nose, sore throat, malaise and other symptoms, most of the new crown pneumonia patients in the early stage of the absence of obvious fever and coughing symptoms, the clinical manifestations of the digestive system such as nausea, vomiting and other symptoms. Due to the different age, the performance of the body may not be the same, some patients have mild respiratory symptoms, while some patients show respiratory difficulties, so we can not determine whether the new coronary pneumonia, new coronary pneumonia determination needs to be combined with the epidemiological history, clinical manifestations, chest imaging and laboratory tests, etc., and the new coronary viruses nucleic acid positive as the main diagnostic criteria. If a sore throat occurs, it is recommended to consult a doctor in a timely manner to identify the causative factors and follow the doctor’s instructions for symptomatic intervention to avoid delaying the condition. Tip: “New coronary pneumonia and new coronary virus pneumonia” mentioned in this article have been renamed to “new coronary virus infection” on December 26, 2022, as announced by the National Health Commission.