There are many lymph nodes in the abdominal cavity of the human body itself, if there are no clinical symptoms and no abnormalities in the examinations, simple lymph node enlargement is not necessarily a manifestation of the disease, and can be followed up and observed by regular ultrasound. The most common abdominal lymph node enlargement is caused by acute enteritis or mesenteric lymphadenitis. First of all, you should pay attention to diet and hygiene in daily life, avoid overeating, eating spicy, greasy, cold and other stimulating foods. If acute inflammation occurs, sensitive antibacterial drugs need to be taken for treatment, such as oral norfloxacin or levofloxacin. When the symptoms are obvious, intravenous drip can also be used for treatment, and when the diarrhea symptoms are more serious, montelukast can also be applied to stop diarrhea. For the case of abdominal lymph node enlargement which is more obvious and the aspect ratio is more than 1, if lymphoma or metastatic cancer is considered, further relevant examination should be done to clarify, such as gastroscopy, electronic colonoscopy and PET-CT. For patients with lymphoma, it is still recommended to be able to puncture biopsy for pathology to further radiotherapy, while for patients with metastasis or regional lymph node metastasis, radical surgical resection with regional lymph node dissection should be considered firstly to obtain better long-term survival results.