HFMD is an infectious disease caused by enterovirus. There are more than 20 types of enterovirus that cause HFMD, among which Coxsackievirus A16 (Cox A16) and enterovirus 71 (EV 71) are the most common. Most children under the age of 5 years old present with mouth pain, anorexia, low fever, small herpes or ulcers on the hands, feet and mouth. Individual children with severe disease develop rapidly, leading to death. There is a lack of effective therapeutic drugs and the main symptomatic treatment. Without complications, the prognosis of the disease is generally good, and most of them are cured within a week. The main treatment is symptomatic. 1, first of all, isolate the affected children, contact should pay attention to disinfection isolation, to avoid cross-infection. 2, symptomatic treatment, good oral care. If the herpes and ulcers in the mouth are serious, gargle or paint the affected area with rehabilitative new liquid, or use a cotton swab to put on the ulcerated surface after meals by mixing Similac into a paste. 3, clothes, bedding should be clean, comfortable, soft clothing, often changed. 4, cut the baby’s nails short, wrap the baby’s hands if necessary to prevent scratching the rash 5, the rash on the hands and feet can be coated with glycomet lotion at the beginning, to be herpes formation or herpes rash broken can be coated with 0.5% iodine volt. 6.Babies with rashes on the buttocks should always clean up their urine and stool to keep the buttocks clean and dry. 7.Anti-viral drugs and herbal medicines can be taken to clear heat and detoxify the body, and vitamin B and C can be added. Prevention 1. Wash your child’s hands with soap or hand sanitizer before and after meals and after going out, do not let children drink raw water or eat cold food, and avoid contact with sick children. 2. Caregivers should wash their hands before touching children, after changing diapers or handling feces, and dispose of dirt properly. 3.Bottles and pacifiers used by infants and children should be washed well before and after use. 4. During the epidemic period, children should not be taken to public places with poor air circulation, and attention should be paid to maintaining household sanitation, frequent ventilation of the living room, and regular drying of clothes and blankets. 5. Children with symptoms should go to medical institutions promptly. Parents should dry or disinfect the child’s clothes and disinfect the child’s feces in a timely manner; children with minor illnesses do not need to be hospitalized and should stay home for treatment and rest to reduce cross-infection. 6. Wash and disinfect toys, personal hygiene utensils, tableware and other items daily.