Itchy bumps on the ankle, consider the following possibilities: the first possibility is nodular itchy rash, you can apply fluticasone propionate ointment, or mometasone furoate ointment 1 day once a day, after applying and then wrapped in plastic wrap for sealing treatment, and then remove it in 20 minutes. And you can take oral levocetirizine hydrochloride capsule 5mg once a day, combined with compound glycyrrhizin capsule 3 times a day, 2 capsules once for treatment. If the effect is not very satisfactory, it can also be treated by applying liquid nitrogen by freezing to make the large nodules necrotic and fall off. The second situation is the emergence of eczema, mainly due to allergies, in addition to small bumps can also appear small blisters, papules such as this, at this time you can take oral avastin tablets 3 times a day, 1 time 1 tablet, topical dinexed cream 1:1 mixed with butyl flufenamic acid cream to treat.