Taking one spironolactone tablet a day can also have some side effects, but they are generally not serious due to the small dose. Spironolactone can act on aldosterone receptors at the end of the distal tubule and in the collecting ducts, blocking Na⁺-H⁺ and Na⁺-K⁺ exchanges, increasing the efflux of water, Na⁺, and Cl-, decreasing the efflux of K⁺, H⁺, and M⁺, and decreasing the efflux of K⁺, H⁺, and M⁺. , decreasing the excretion of K⁺, H⁺, Mg²⁺, and serving the purpose of potassium preservation and diuresis. It is used clinically to treat refractory edema associated with elevated aldosterone, such as refractory cardiogenic and renal edema, and cirrhotic ascites. The most common adverse reaction after using this drug is hyperkalemia, especially for patients who use the drug alone, there will also be nausea, vomiting, stomach cramps, hyponatremia, hair growth, gynecomastia, headache, drowsiness, etc. Therefore, taking one tablet of spironolactone a day will also have certain side effects, but due to the small dosage of one tablet a day will not usually have serious effects. Allergic to the drug, hyperkalemia of the population prohibited the drug treatment; need to use spironolactone treatment patients are recommended to use the drug under the guidance of a doctor, do not self-administer the drug.