Rabeprazole can be stopped suddenly, when there are adverse reactions such as nausea, rash, need to stop the drug immediately, but no adverse reactions, need to follow the doctor’s advice to take. Rebeprazole sodium enteric-coated tablets can attach to the surface of the cells of the stomach wall after taking, inhibit the secretion of gastric acid by inhibiting the enzyme, and are used for peptic ulcer as well as reflux esophagitis. Normal patients after taking the drug for a period of time suddenly stop, short-term gastric acid may rise, thus aggravating the condition, so it is necessary to follow the doctor’s advice according to the course of treatment. However, when patients experience adverse reactions such as nausea, rash and headache, abdominal distension, constipation, diarrhea, epigastric pain, elevation of transaminases and bilirubin, the drug should be immediately discontinued and other reasonable treatment should be taken. Rabeprazole treatment of gastritis, peptic ulcer, gastroesophageal reflux disease and other diseases, according to the course of treatment, to the course of the direct discontinuation of the drug, the existence of individual cases of as-needed to take, generally do not appear to be a sudden discontinuation of the drug problem, but for the patient whether to stop the drug, it is recommended that it is best to go to the hospital as soon as possible to consult the doctor’s professional opinion, so as not to cause serious effects.