The tingling of bitter ginseng gel injected into the vaginal area is considered to be related to the presence of broken vaginal mucosa, congestion, drug irritation and allergy to bitter ginseng gel. Bitter ginseng gel is mainly used for the treatment of vaginal inflammation, including bacterial vaginitis and mycotic vaginitis, etc. The gel preparation is more conducive to the absorption of the vaginal mucosa. Due to the inflammation of the vagina, the vaginal mucosa is congested and swollen, so after injecting bitter ginseng gel, there is a possibility of burning pain or tingling in the vagina for a short period of time, but the symptoms will disappear after a period of adaptation. However, the possibility of allergy after the use of bitter ginseng gel cannot be ruled out. In case of allergy, the vagina may become congested, swollen, excessively itchy and painful, and in case of systemic symptoms, the skin may also develop maculopapular rash, which requires immediate cleaning of the gel medication in the vagina and, if necessary, anti-allergy medication to relieve the symptoms.