How much is a shot of plague vaccine is related to the local economic level and the grade of the hospital, and the general price is around 100~300 dollars. It is recommended to consult local medical institutions for specific prices. Vaccine cost will be determined by the local economic situation and hospital level and other factors, if in the general county and city areas, due to the lower level of consumption, the general plague vaccine in the case of non-tertiary hospitals in about 100 yuan. In first-tier cities with higher economic level, the price charged by some third-class hospitals may be higher, and a shot of plague vaccine is around 300 yuan. Bubonic plague is mainly spread by rodents, such as rats, and can be transmitted through the bite of rat fleas, etc. It is highly contagious. Usually patients will have symptoms such as pneumonia, swollen and painful lymph nodes, and fever. If symptoms of plague infection appear, you should go to the hospital immediately to avoid delaying your condition.