Treatment of colitis includes: first, control of inflammatory response, application of 5-aminosalicylic acid drugs, including liuzosulfapyridine, olsalazine, mesalazine and other drugs; second, glucocorticoids have better efficacy in acute exacerbation; third, immunosuppressant, mercaptopurine can be applied to chronic persistent cases that are ineffective on hormone therapy and hormone-dependent. Symptomatic treatment, timely correction of water-electrolyte balance disorders, anemia can be transfused, hypoproteinemia should be supplemented with albumin, severe cases should be fasting, complete extragastrointestinal nutrition therapy. Patient education: patients in the active period should have sufficient rest, regulate their emotions and avoid excessive psychological pressure. Fluid and semi-fluid diet can be given in the acute period, and then changed to nutritious, easy-to-digest, less-slag diet after the condition improves. For patients with combined ulcers, perforation, bleeding and suspected malignancy, surgical treatment is needed.