Anticoagulants are usually required all the time after recovery from a cardiac brain attack, whereas non-cardiac brain attacks usually do not. Patients with cerebral infarcts take anticoagulants, primarily for those with cardiogenic brain infarcts. The aim of anticoagulation is to prevent the formation of new intracardiac thrombi and to prevent the spread of secondary thrombi at the site of embolism, thus enabling the prevention of cardiogenic cerebral embolism. It needs to be carried out after assessment by a clinician. Commonly used anticoagulants include warfarin, rivaroxaban, and dabigatran etexilate. Taking anticoagulants can effectively reduce the recurrence rate of cerebral infarction, but they are also prone to cause bleeding, which requires close monitoring of the patient’s coagulation function and appropriate medication adjustments under the guidance of a physician to circumvent the risk of bleeding. Cerebral infarction of non-cardiac origin mainly refers to the formation of cerebral thrombosis, therefore, anticoagulation is usually not required, and antithrombotic therapy is needed, and commonly used drugs include aspirin and clopidogrel. For patients with cerebral infarction, it is recommended to follow up regularly in the neurology clinic, and do not arbitrarily adjust the medication or discontinue the medication on your own.