Uremia cannot be cured, uremia is the end stage of chronic renal failure, uremic phase, this period of the kidneys appear sclerosing nephropathy, irreversible loss of kidney units and kidney function. There is no drug treatment to reverse uremia, which is the positive blood pressure, reduce proteinuria, correct anemia, correct low calcium, high phosphorus, hyperparathyroidism. Once the symptoms of uremia, uncontrollable heart failure, gastrointestinal symptoms, nausea and vomiting that cannot be improved by limiting protein intake, uremic encephalopathy, hyperkalemia that is difficult to correct, metabolic acidosis that is difficult to control, it is time to perform renal replacement therapy, hemodialysis or peritoneal dialysis treatment, and actively treat the complications associated with dialysis, and if the patient has the conditions for kidney transplantation conditions, kidney transplantation can be performed for treatment.