Itchy and painful skin may be related to eczema, contact dermatitis, herpes zoster and so on. 1. Eczema: mainly due to heredity, immune abnormalities, abnormal hormone levels, endocrine and metabolic diseases, etc., diet, mental factors, etc., can also trigger the disease, often showing erythema, rashes, blisters, vesicles, etc., which may lead to the appearance of itchy and painful skin. 2. contact dermatitis: mainly due to skin contact with exogenous substances, skin irritation caused by, often showing erythema, swelling, papules, blisters, etc., may lead to itchy and painful skin. 3. Herpes zoster: mainly caused by viral infection, low immunity, mental stress, etc. will also induce the disease, often showing a band-like distribution of blisters, pain, etc., may lead to the appearance of the skin and itchy and painful situation. Therefore, there are more reasons for itchy and painful skin, it is recommended to visit the hospital in time to identify the cause and follow the doctor’s instructions for targeted treatment.