Normal urine microalbumin and elevated urine microalbumin and creatinine ratio may be affected by urine dilution when detecting urine microalbumin alone, while the test result of the ratio of the two can eliminate the influence of urine dilution and get a more accurate test result. Early lesions in patients with kidney disease can lead to increased urinary microalbumin, which is an early and important sign of glomerular damage, but the detection of urinary microalbumin alone may be interfered by factors such as exercise, urine concentration and dilution, resulting in inaccurate results, especially if the urine is diluted, it is easy to have a normal urinary microalbumin and increased urinary microalbumin and creatinine ratio. Therefore, it is generally recommended to test urine microalbumin and creatinine ratio, which can eliminate the interference of many influencing factors and reflect early glomerular lesions more accurately and sensitively. If the test found that the urine microalbumin and creatinine ratio is elevated, it is recommended to go to the regular hospital in time, further improve the relevant examination, and make a clear diagnosis, do not blindly careless, so as not to delay the condition.