There are certain grades of hypertension, more severe blood pressure is defined as blood pressure above grade 2 hypertension, that is, blood pressure more than 160/100mmHg, for this relatively high hypertension patients, medication should first choose a compound preparation, that is, the application of drugs such as valsartan hydrochlorothiazide tablets, Irbesartan hydrochlorothiazide or valsartan amlodipine for treatment to bring blood pressure quickly to the specified target, it is recommended to Blood pressure control below 140/90 mmHg. Some patients may have better blood pressure regulation and may be able to lower their blood pressure to normal with a single medication, such as nifedipine alone, such as Bactrim or Nifedipine, or the patient may be able to use a single medication.