IgA nephropathy is not serious if it only manifests as simple microscopic hematuria or recurrent hematuria, nephrotic syndrome with mild pathological changes, and can be treated in time, and it is serious if the symptoms are difficult to control and the pathological changes are severe. IgA nephropathy is a primary glomerular disease, glomerular mesangial area is dominated by IgA (immunoglobulin A) deposition, IgA nephropathy is often asymptomatic, for the physical examination found that hematuria (and) proteinuria is dominant. In IgA nephropathy, if there is persistent uncontrollable high blood pressure, proteinuria, renal function impairment, renal biopsy shows glomerulosclerosis, interstitial fibrosis, glomerular atrophy, or a large number of crescent formation of pathological changes, the condition of the patient is serious, and the prognosis is poor. It is recommended that patients with IgA nephropathy should consult regular hospitals in time and standardize the treatment under the guidance of physicians.