Itchy skin during exercise may be caused by physiological factors such as elevated skin temperature and sweat stimulation during exercise; it may also be caused by diseases such as cholinergic urticaria. 1. Physiological factors: due to running skin temperature will rise, sweat secretion will increase, which will cause stimulation of the skin surface sensory nerve endings, inducing itchy skin and other symptoms. 2. Cholinergic urticaria: hot bath, exercise, drinking alcohol, eating spicy food, emotional excitement and other reasons may induce cholinergic urticaria, so that the patient appears to have edematous erythema on the surface of the skin, wind, itching and other symptoms. Patients with itchy skin during exercise should rule out physiological factors and then go to the hospital for relevant examinations to clarify the cause of the disease.