Cranial repair is a routine surgery in neurosurgery clinic. There are various risk factors in the current social environment, such as traffic accidents, production safety accidents, falling objects, and some cranio-cerebral diseases that require craniotomy, all of which may cause cranial defects, so cranial bone repair surgery needs to be more widely carried out. Cranial repair is also a surgical procedure with a long history, and was practiced by our ancestors thousands of years ago. After thousands of years of development and evolution, the technique of cranial repair surgery has become very mature in modern medical conditions. With the continuous development and progress of surgical techniques, cranial repair materials are also undergoing constant iteration and renewal, and are also becoming more mature and perfect. At present, the commonly used clinical cranial bone repair materials are mainly titanium mesh materials and polyether ether ketone PEEK materials. So what is the difference between domestic and imported titanium mesh for cranial bone repair? Titanium mesh cranial bone repair materials, the earliest from abroad began to develop. But after decades of development, the current domestic also more popular, domestic titanium mesh material manufacturing and processing technology has been more mature, and imported should not be a significant difference. However, this material itself in fact there are some defects and deficiencies, there may be some problems in clinical applications, such as titanium mesh repair skull after surgery may be infected with the phenomenon of rejection, the phenomenon of material wear and tear of the scalp phenomenon, which can lead to scalp ulceration of the material exposed, there is also a material insulation is not good, the patient may be sensitive to the outside world of the environment of hot and cold discomfort, and in addition to this metal material may be on the patient to accept the CT MRI medical examination impacts. In addition, this metal material may also have an impact on the patient’s ability to undergo CT MRI and other medical examinations. Therefore, it is not recommended to use titanium mesh material for cranial bone repair, domestic and imported are not recommended. At present, there is an emerging clinical material called polyether ether ketone PEEK material. This is a new type of special polymer materials, excellent performance, can be very good to avoid the titanium mesh may produce the above problems, PEEK material in hardness, stiffness, strength, elasticity, thermal insulation, stability, histocompatibility, radiation transmissibility, plasticity and so on are very good, and the autologous skull is basically equivalent to the cranial bone, is the very ideal cranial bone repair materials, by neurosurgeons and patients with cranial defects. It is an ideal material for cranial bone repair and is favored by neurosurgeons and patients with cranial defects. At present, our team is widely using PEEK, an advanced cranial bone repair material, and we are constantly improving and upgrading the technology and optimizing the design of the material, as well as introducing the concept of cosmetic plastic surgery, so as to comprehensively carry out PEEK cranial bone repair and plastic surgery, to achieve good clinical results, which is widely acclaimed and recognized.