Prevention and treatment of upper limb edema after breast cancer surgery

  The upper limb edema is a common complication after breast cancer surgery, mainly due to the following reasons 1. The upper limb is often swollen to different degrees in the early stage after radical surgery or modified radical surgery, and lymphedema can appear in several months or even 20 years later, but 75% occurs in the first year after surgery. In China, it was reported that 10% of patients had upper extremity lymph node edema after radical breast cancer surgery, and 59% had “moderate and mild” edema, which could be aggravated by post-radiotherapy and postoperative infection. The incidence of lymphedema after breast cancer surgery was 24% in the 1990s and 28% in 1249 cases after 9.5 years of follow-up according to Mo rt imer.  The etiology and pathophysiological mechanisms of the occurrence are still unclear, and most of the literature suggests that it is due to an obstruction or interruption of the lymphatic return pathway in the upper extremity, resulting in an increase in the protein content of the interstitial fluid and causing a series of pathogenic changes.  Treatment is more difficult: (1) apply soft pillows to elevate the affected limb, and massage by manipulation, pushing from distal to proximal with certain pressure for 15 minutes each time, 3 times a day.  (2) axillary area and upper limb heat therapy: with physical heating method, infrared and microwave, etc., with massage effect.  (3) Ganglion closure: The purpose is to release the spasm of blood vessels and lymphatic vessels and improve the circulation function, with an efficiency of 63%.  (4) Surgical treatment: Extensive excision of the subcutaneous tissue and deep fascia of the diseased upper limb, so that the skin lymphatic vessels are connected with the muscle lymphatic vessels.  (5) Appropriate due to diuretics.  (6) Chinese medicine treatment: 30 grams each of centipede, turtle, whole lizard and stiff silkworm, dried into powder, 5 grams each time, 3 times a day, taken orally. The above prescriptions need to be applied under the guidance of herbalists.  2.Infectious edema, caused by bacteria, viruses, etc. This condition is mostly found in limb trauma, or a decrease in human resistance function, clinical manifestation of inflammatory reaction symptoms and signs, and can be treated with antibacterial drugs with good effect.  3, obstructive edema: mainly caused by obstruction of vascular or lymphatic reflux, which may be caused by embolism or tumor. Embolism can be treated with thrombolytic therapy. Tumor compression may be caused by tumor recurrence or metastasis, and then treatment needs to be based on the situation, which can be chemotherapy or radiotherapy, surgery, etc. Firstly, it should be confirmed by examination such as sex CT or biopsy, and treatment may not be in doubt.  As lymphedema is difficult to treat, the current treatment is based on prevention, mainly on the following points 1. mitigate surgical damage, sentinel lymph node biopsy is the most effective technique to avoid upper limb lymphedema.  2, appropriate and correct exercise, postoperative functional exercise should be gradual and avoid overexertion of the affected limb. Control weight and reduce lymphatic load.  3.Avoid unnecessary radiotherapy. If low-risk patients with 0 or 1-2 axillary lymph node metastases, postoperative radiotherapy in the axillary area should be avoided as much as possible, and even if it is needed, the radiation dose should be designed and allocated.  4.Avoid injury to patients Pay attention to warmth and protection, avoid venipuncture, intravenous infusion and blood pressure measurement of the affected limb.  5.Prevent infection of the affected limb. Repeated episodes of cellulitis are the main cause of aggravating lymphedema. Patients with rash and redness, along with fever of 38 degrees or more, should be seen in hospital.