Most of the treatments for cholangiocarcinoma adopt surgery as the mainstay, supplemented by radiotherapy, chemotherapy, immunotherapy and so on.
There is no clinical evidence to show the specific cause of cholangiocarcinoma. After diagnosis, it is necessary to improve relevant examinations, such as MRCP, enhanced CT, liver function, cardiopulmonary function evaluation, etc., to determine whether surgical treatment is feasible.
The principle of treatment is mainly based on surgical intervention, with postoperative adjuvant radiotherapy and chemotherapy to improve the surgical effect. Surgical protocols generally include pancreaticoduodenectomy, mid-bile duct resection, etc.; chemotherapeutic drugs include cisplatin, gemcitabine, etc.
For patients whose tumors have progressed to advanced stages, where surgery is of little significance or cannot tolerate surgery, biliary drainage can be performed to control biliary infection, improve liver function, reduce comorbidities, and radiotherapy to achieve the purpose of improving quality of life and prolonging survival time as much as possible.
Biliary drainage includes percutaneous hepatic biliary drainage, gallbladder puncture drainage, ERCP stent implantation, etc.; biliary infection control drugs include cefoperazone, moxifloxacin, etc.; to improve liver function, drugs include compound glycyrrhizin, adenosylmethionine butanedisulfonate tablets, etc.
It is recommended to consult a professional doctor in a regular hospital for specific treatment plan, and follow the doctor’s instructions for medication and surgical treatment.