Lenopril and perindopril belong to the 3rd generation of angiotensin-converting enzyme inhibitors, and it is not possible to evaluate which one is more advanced, but only to consider which one is more suitable for patients. Lenopril and perindopril are commonly used antihypertensive drugs, the main role is to inhibit angiotensin-converting enzyme inhibitors, the two drugs belong to the same generation of antihypertensive drugs, antihypertensive mechanism is similar, there is no difference between good and bad. Angiotensin-converting enzyme, although the role of similar, but clinically there are a number of varieties, different varieties may be suitable for different individuals, antihypertensive effect may also appear differences. Patients with hypertension should pay attention to the antihypertensive effect and adverse reactions of the drugs when choosing lynopril and perindopril. The adverse reactions include cough, headache, dizziness, constipation, anxiety, nausea, dyspnea, etc. It is forbidden to use it for patients who are allergic to the components of the drug or hyperkalemia, so it is important to use the drug under the guidance of a professional physician.