Low back pain after getting up in the morning is clinically common in two diseases. The first common disease is urinary stones, which can cause pain and discomfort in the lower back, even accompanied by perineal distension, especially when urinating, and requires further urological ultrasound for a clear diagnosis. The pain can be relieved by pain medication when it is obvious. Smaller stones are treated with medication for stone removal, while larger stones require lithotripsy or even surgery. The second common disease is acute appendicitis with embedded stones, which can cause pain and discomfort due to the posterior position of the appendix, which can irritate the psoas major muscle. It is necessary to perform appendiceal ultrasound examination combined with routine blood tests to clarify the diagnosis, and after the diagnosis is clear, it is necessary to perform appendectomy to achieve the purpose of cure.