(Disclaimer: This article is for scientific use only. To protect patient privacy, the relevant information in the following content has been processed.) Abstract: This is a presentation of an 80-year-old patient who presented to the hospital with recurrent blood in the stool. Based on the medical history and ancillary examinations, the clinical diagnosis was tubular choriocapillary adenoma, which is a tubular choriocapillary adenoma of the descending colon because it occurred in the descending colon area. Due to the multiple polyps in the descending colon, he came to the surgery department to seek new treatment because of the difficulty of resection under colonoscopy. With the joint efforts of us and the family, the patient completed laparoscopic resection of the descending colon tumor, and the surgery recovery was smooth and the postoperative recovery was good. [Basic information] Male, 80 years old [Disease type] Tubular villous adenoma of descending colon [Hospital] Hefei Second People’s Hospital [Consultation date] July 2021 [Treatment plan] Laparoscopic partial resection of descending colon + lumpectomy of descending colon with lateral anastomosis [Treatment cycle] Hospitalization for 11 days, colonoscopy after 10 months [Treatment result] Good surgical result, no serious complications, postoperative reexamination In March 2021, the patient began to have frequent blood in the stool, mostly fresh blood, and the blood mixed with stool, without There was no abdominal pain or thinning of the stool. Due to professional sensitivity, the patient was given an anal finger examination in the outpatient clinic, which did not reveal any significant abnormalities. The largest remaining polyp was about 40 cm from the anal verge, with a diameter of about 3.5 cm and a broad-based polyp, which was difficult to remove under colonoscopy. The patient was admitted to the outpatient clinic with adenomatous polyps of the descending colon. After admission, the patient’s cardiopulmonary function was further evaluated because of the possibility of surgical treatment, and cardiac ultrasound, ambulatory electrocardiogram and pulmonary function tests were completed. At the same time, enhanced CT of the chest and abdomen was completed to rule out any tumor recurrence. No metastasis or recurrence of malignant tumor was found in any of the examination results, and there were no obvious contraindications to surgery in the cardiopulmonary function examination. We then communicated with the family about the patient’s condition, and considered that the polyps were benign, and for such tumors, most of them were chosen to be resected by colonoscopy, but since the patient had already tried endoscopic resection, which was risky, we considered laparoscopic surgical resection in surgery, which had the benefit of more thorough treatment. The surgery was finally performed with the consent of the family. Then a laparoscopic partial resection of the descending colon was performed at 3 cm along the upper and lower margins of the tumor after colonoscopic localization. Due to the patient’s obesity, it was more difficult to make an in vitro anastomosis, so a laparoscopic lateral anastomosis of the descending colon (OverLap anastomosis) was done. The patient’s surgery went well and the operation time was 120 minutes. The patient recovered well after the operation and was discharged from the hospital, and was advised to review the patient regularly. The patient’s anus was exhausted on the second day after the operation, and he could eat liquid food without residue from the third day after the operation, and there was no blood in the stool after the operation, and the stool was also formed. Ten months later, the patient came to the outpatient clinic for a follow-up examination, and a colonoscopy was arranged, which showed that the anastomosis was open and no recurrence of polyps was observed, but two hyperplastic polyps were found, which were then removed. The patient was very happy about the good result of this operation. However, since the patient has a history of colon cancer and more than 10 polyps were found in the colon 6 years after colon cancer surgery, the possibility of recurrence of polyps is considered to be high, therefore, regular follow-up visits to the hospital are needed. stool routine and occult blood are checked once every 3 months and colonoscopy is repeated once a year. In addition, since the patient has experienced surgery and chemotherapy, the immunity is reduced, so it is recommended that the patient should ensure adequate nutrition and a balanced diet with more fruits, vegetables and other foods rich in dietary fiber. It is also important to avoid tobacco and alcohol and other products that are irritating to the intestinal tract. It is also important to get enough sleep, not to strain, and to maintain an optimistic state of mind to help the recovery of the disease. V. Personal insight Throughout the consultation process, the patient’s condition gradually improved after active surgical treatment. In this case, we can note that the patient had a history of colon cancer, but she did not undergo routine review after surgery and did not detect the polyps in the intestine at an early stage, which led to the gradual aggravation of her condition. This time, the patient sought medical examination because of repeated blood in stool, so that it was found in time, and if the blood in stool is serious without timely consultation may lead to polyp malignant transformation. Therefore, for any disease, early detection and early treatment are still the key to improve the cure rate of the disease. Patients are advised to follow up and review the disease on time, and to strengthen nutrition and exercise in daily life to prevent recurrence.