Rash on toes may be due to contact dermatitis, insect bite dermatitis, tinea pedis and other factors, and its treatment includes general treatment and medication. 1. Contact dermatitis: some patients may be in contact with allergens or irritants, resulting in allergic or irritant symptoms of red rash on the toe area, at this time, you can use topical glycerine lotion, mometasone furoate cream, oral loratadine, cetirizine and other antihistamines, so as to improve the symptoms. At the same time to avoid the causative factors. 2. Insect bite dermatitis: mostly seen in summer, due to mosquito bites on the toes, thus causing the part of the red rash, accompanied by itching. Zinc oxide ointment, hydrocortisone butyrate cream can be used externally to relieve itching, and at the same time to ensure that the surrounding environmental hygiene, if necessary, can be done to kill insects. 3. Tinea pedis: This is a fungal infection caused by dermatophytes, which can also cause a red rash on the toes. After diagnosis, you can cooperate with the doctor to choose ketoconazole, econazole, clotrimazole and other antifungal drug treatment, so as to eliminate the symptoms of red rash on the toes. There may be other reasons for the rash on the toes, so you need to cooperate with your doctor to complete the examination and determine the cause, and then do the targeted treatment and therapy. The above drugs should be used in accordance with medical advice.