For women who experience menstrual cramps with menstruation, you can usually apply the menstrual cramp patch locally on the lower abdomen, usually directly on the underwear, rather than directly on the woman’s skin, because some menstrual cramp patches may be more irritating, and they need to be separated from the skin, and applying them directly on the underwear will be able to assist in relieving the pain. Since the severity of menstrual cramps varies from woman to woman, the use of the patches alone may not always provide good pain relief. Some women with severe menstrual cramps need to consider taking painkillers for symptomatic pain relief, such as ibuprofen extended-release capsules.