Candesartan and amlodipine benzenesulfonate tablets can be mixed when there are drug indications. Candesartan is mainly used for the treatment of primary hypertension and other diseases; amlodipine benzenesulfonate can be used for the treatment of hypertension, chronic stable angina, variant angina and other diseases. Both drugs belong to antihypertensive drugs, if after taking a drug alone antihypertensive treatment, can not achieve the ideal range of blood pressure reduction, then you can choose to take these two antihypertensive drugs combined antihypertensive treatment. Candesartan and amlodipine benzenesulfonate can be mixed to achieve the desired antihypertensive effect when they have drug indications or when they meet the principle of combined use. However, for the presence of severe hypotension, severe aortic valve stenosis, severe hepatic and renal insufficiency, can not be combined with these two drugs mixed. Candesartan may cause angioedema, syncope, acute renal failure, liver function deterioration, hyperkalemia and other discomforts after use; it is forbidden for those who are allergic to the components of the drug and those with bile stasis, and in the process of using the drug, it is necessary to review liver and kidney function regularly and monitor blood pressure regularly, while pregnant women, breastfeeding women and other special groups of people need to be guided by a doctor to use the drug. Amlodipine benzenesulfonate tablets after the use of flushing, fatigue, edema, abdominal pain, nausea and other discomforts, allergic to dihydropyridines, severe aortic stenosis is prohibited; need to monitor the blood pressure in the process of using the drug, to avoid causing hypotension, and children, the elderly and other special groups, need to be under the guidance of a doctor to use the drug. All of the above medications should be used under the guidance of a doctor, avoid self-medication to avoid adverse consequences.