Pimples on earlobes are commonly caused by folliculitis, epidermal cysts, boils, keloids, etc. It is necessary to take medication, surgery, physical therapy, etc. to remove them for specific diseases. 1. Folliculitis: after the diagnosis of this disease, you need to use topical antibiotic treatment, such as erythromycin ointment, mupirocin ointment, etc.; the effect of topical drug treatment is not good, oral antibiotic treatment, such as doxycycline, minocycline, etc.; such as fungal infections, but also the use of antifungal drugs, such as ketoconazole, terbinafine and so on. 2. Epidermal cysts: this disease mainly takes surgical treatment to remove the cysts; if there are secondary bacterial infections, antibacterial treatment is needed, such as fusidic acid cream, compound polymyxin B ointment, etc.; when the inflammation is more serious, it can be injected into the lesion with glucocorticosteroid treatment, such as prednisone. 3. Boils: usually the condition is not serious, boils can form pus embolism, self-shedding, do not need special treatment; if the condition is more serious, topical antimicrobial treatment, such as fusidic acid cream, compound neomycin ointment, etc.; when the effect of local treatment is not obvious, oral antimicrobial treatment, such as oxfloxacin, erythromycin, etc.; if necessary, surgical treatment, physical therapy, and so on. 4. Keloid: The raised scar formed during the healing process of skin injury can be treated by post-surgical millilayer X-ray irradiation or local skin lesion hormone injection. It is recommended that the patient combined with their own situation, timely to the regular hospital dermatology consultation, clear diagnosis, follow the doctor’s instructions and active treatment. Drugs need to be used under the guidance of a doctor, not blindly self-medication.