The following indicators are scored: Joints involved (0-5) 1 large joint 0 2-10 medium to large joints 1 1-3 small joints 3 More than 10 joints 5 Serology (0-3) Negative for rheumatoid factor and anti-cyclic citrulline (CCP) antibodies 0 Weakly positive for rheumatoid factor and anti-cyclic citrulline (CCP) antibodies 1 Strongly positive for rheumatoid factor and anti-cyclic citrulline (CCP) antibodies 3 Synovitis Duration (0-1) Less than 6 weeks 0 Greater than or equal to 6 weeks 1 Acute phase reactants (0-1) Normal C-reactive protein and sedimentation 0 Elevated C-reactive protein and sedimentation 1 Total cumulative score greater than 6 or more, definite diagnosis of rheumatoid arthritis