There is no such thing as the best treatment for enlarged prostate with calcification. The treatment of enlarged prostate with calcification needs to be judged according to age and condition, and can usually be treated by regular review, medication and surgery. 1. Patients younger than 45 years old who do not have any conscious symptoms, such as frequent urination, urinary urgency, dysuria, etc., can choose to undergo regular review and observation. Regular checkups and observation are sufficient, and generally no medication is used for treatment. 2. Patients over 45 years old, if there are symptoms such as urinary effort, urinary diversion, urinary pain and so on. Oral alpha-blockers such as prazosin, doxazosin, tamsulosin, etc. can be chosen. 3. For patients over 60 years old, if they have symptoms such as difficulty in urination and obstruction, they usually choose to undergo prostatic hyperplasia electrosurgery treatment, which can completely cure enlarged prostate with calcification. In addition, it is recommended that patients with enlarged prostate with calcification go to the hospital in a timely manner, do the relevant examination, clarify the cause of the disease and then follow the doctor’s instructions for targeted treatment.