Drug therapy is the most basic and commonly used method of pain treatment. Pain medications have different drug choices and dosing intervals according to different diseases, and commonly used drugs are divided into non-narcotic analgesics and narcotic analgesics, with non-narcotic analgesics mainly referring to non-steroidal anti-inflammatory drugs and narcotic analgesics including weak opioid analgesics and strong opioid analgesics. The specific use should determine the dosage and administration interval according to the patient’s symptoms, effective drug concentration and half-life. It is also necessary to pay attention to the patient’s mental state and try to achieve the best effect with the smallest dose of drugs. Non-steroidal analgesics: 1. aspirin: a derivative of salicylic acid, recommended to be taken at an interval of 4 hours according to medical advice, not to be used without authorization; 2. indomethacin: an anti-inflammatory analgesic of indole class, recommended to be taken at an interval of 8-12 hours according to medical advice, not to be used without authorization; 3. ibuprofen: a derivative of propionic acid, recommended to be taken at an interval of 12 hours according to medical advice, not to be used without authorization; 4. diclofenac sodium: a derivative of phenylacetic acid, recommended to be taken at an interval of 12 hours according to medical advice, not to be used without authorization; 4. Phenylacetic acid derivatives, recommended to be taken at intervals of about 12 hours as prescribed by the doctor, not to be used without authorization; 5, Ketorolac: Pyrrolizidine derivatives, recommended to be taken at intervals of 12 hours as prescribed by the doctor, not to be used without authorization; 6, Piroxicam: Enolic acid derivatives, recommended to be taken at intervals of 12-24 hours as prescribed by the doctor, not to be used without authorization; 7, Meloxicam: Enolic acid non-steroidal anti-inflammatory drugs, recommended to be taken at intervals of 24 hours as prescribed by the doctor, not to be used without authorization It should be taken at 24-hour intervals and should not be used without authorization. Weak opioid analgesics: such as tramadol, these painkillers are moderate painkillers, tramadol is recommended to be taken as prescribed by the doctor, and the specific interval is decided by the doctor. Third, strong opioid analgesics: such as morphine, oxycodone, etc., the pain-relieving effect is better, and it is required to be taken as prescribed, with specific intervals to be judged by the doctor. Analgesics must be taken in strict accordance with the instructions, and the time of taking painkillers also has a certain relationship with the speed of metabolism of drugs in the body, and needs to be taken in accordance with medical advice. Because of the large side effects of painkillers, analgesic treatment must be carried out under the guidance of a doctor, and the dosage of drugs should not be increased or the duration of use extended at will.