Erythromycin ointment is a topical antibiotic that can be used to rub the inside of the nose if the patient is not allergic to the erythromycin component. The clinical application mainly includes the following aspects: the first is for patients with nasal bleeding, which may be a local breakdown of the nasal cavity, erythromycin ointment can be applied to the bleeding area to promote the healing of the mucosa and reduce the infection in the local breakdown. The second is for patients with dry rhinitis, mainly dryness, erosion and ulceration of the nasal mucosa, applying erythromycin ointment can reduce the local inflammatory reaction and promote the healing of the wound as soon as possible to reduce the patient’s pain. The third patient, such as fire or bacterial infection in the nasal cavity, induced nasal vestibule boils or folliculitis and other such diseases, the application of erythromycin ointment can play an anti-inflammatory and pain-relieving role. All in all, erythromycin ointment rubbed inside the nose is a frequently used method, with fewer side effects and generally milder reactions, while also achieving the purpose of treating the disease.