Epilepsy is a relatively common disease in childhood, with about 400,000 new patients each year, and children account for most of them. Many people are afraid to try to use them because they are worried about the adverse effects of the drugs, or even that their children will become stupid after taking them, and do not give them regular treatment, delaying the treatment. There is often a tendency for epilepsy to worsen and become difficult to control if the correct intervention is not given, so once diagnosed early it is still important to treat it formally as early as possible. Not all epilepsy treatments require the selection of antiepileptic drugs, and depending on the cause of the disease, we choose treatment options differently, but it is still necessary to use antiepileptic drugs when they should be used. This involves the etiological diagnosis of epilepsy, and the pinyin of epilepsy is also more complex involving genetic infection metabolic immune structural abnormalities of the brain, and unknown causes. For different etiologies. We can choose different cause-specific treatment modalities. For example, if we clearly have pyridoxine-dependent epilepsy, it is treated with long-term high-dose oral vitamin B6. If it is a glucose transporter 1 deficiency syndrome, it is treated with a ketogenic diet. If imaging of the head reveals abnormalities in structures such as intracranial occupancy, gray matter heterotopia, and limited cortical dysplasia, the treatment of choice is surgery. However, when we cannot find a clear cause of epilepsy, or it is an idiopathic or cryptogenic epilepsy, medication is the basic treatment and is an essential treatment. Anti-epileptic drugs, divided into traditional anti-epileptic drugs and new anti-epileptic drugs, traditional anti-epileptic drugs include phenobarbital, clonazepam, carbamazepine, phenytoin sodium, valproic acid, etc. The newer Kantian drugs include oxcarbazepine, levetiracetam, lamotrigine, tolterazide, lacosamide, and pirampanel. Compared with traditional antiepileptic drugs, the newer antiepileptic drugs do not have a significant advantage in terms of epilepsy cure rate, but they do have a significant advantage in terms of incidence of adverse effects and tolerability of oral medications. Indeed, as parents fear. All antiepileptic drugs have a range of adverse effects, such as effects on the hematologic system, effects on liver function, effects on cognition, endocrine effects, and reproductive teratogenicity. However, the occurrence of these adverse reactions is a probability event, and they have a low probability of occurrence in all studies. In the process of using antiepileptic drugs, we should regularly review and monitor the occurrence of adverse drug reactions, and intervene as early as possible once they occur. We should weigh the pros and cons and start regular treatment for the child as soon as possible after diagnosis, and choose an appropriate medication according to the child’s age, gender, and cognitive level. Finally, we must believe that epilepsy is a treatable disease, and most of them are curable as well. Work together.