Every year in summer, the hospital’s dermatology outpatient disease will appear again as scheduled a seasonal disease – papular zoster measles. The seasonal, good in the lower limbs and waist and buttocks, the clinical manifestations are mainly bright red pimple-like papules, pimple pimple tip can often be seen pinpoint hemorrhage points, and even blisters. The itching is obvious, which has a great influence on people’s daily life. The old and new rashes often exist at the same time; a small number of patients with recurrent episodes, more stubborn, also known as itchy rash; serious patients can continue to patients teenagers, adults. People with allergies are more prone to the disease, and the lesions are more severe. Patients commonly come to the hospital when the itching is intolerable. Papular urticaria has the characteristics of recurrent attacks and high morbidity. The name “papular urticaria” originates from the 19th century, when the exact cause of the disease was not known and it was named based on its morphological features. The main hypotheses for the etiology of the disease include insect bites, digestive disorders and food allergies, infections, and neuropsychiatric factors. Since the middle of the last century, more and more evidence found that the allergy caused by insect bites is the cause of the disease, while the other three types of hypotheses have not been supported by strong evidence, and their guidance of clinical treatment and prevention of the disease is often ineffective, while the treatment and prevention based on the theory of insect bites have received good results, and the skin lesions often stop recurring after patients leave the environment. Moreover, it is found that the seasonal fluctuation curve of the incidence of this disease is quite consistent with the change of insect breeding and reproduction, with the highest in summer and autumn, and many patients leave their environment (after hospitalization) and the condition is quickly cured; and after spraying insecticides such as dichlorodiphenyltrichloroethane (DDT) and disinfecting and killing pets in the residence of the patients, the lesions can quickly stop recurring, and according to the digestive dysfunction and food allergies, infections, etc., treatment is often ineffective, and digestive disorders and food allergies, infections and so on, the cause of the disease. Treatment can not be effective, and digestive disorders and food allergies can not explain the seasonality of papulopapular measles, large differences in the incidence of the year, as well as the rapid disappearance of symptoms after hospitalization of children with the onset of symptoms and other phenomena. Therefore, more and more scholars believe that insect bites, especially arthropod bites, are the only cause of papulopapular measles. More than 50 years of domestic and foreign literature suggests that papular urticaria may be due to insects, especially a variety of arthropod bites, including: fleas, various mites (grain mites, avian mites, animal mites, chiggers, autumn harvest mites), mosquitoes, bedbugs, etc., arthropods bite their saliva protein and other insect proteins can cause allergic reactions, allergic insect proteins can be transmitted with the blood circulation pathway caused by the non-bite at the Skin lesions. Children’s skin is more tender, sensitivity is higher, after biting the insect salivary protein and other heterologous eggs from the human body, the initial sensitization time is about 10d, after biting again that is the emergence of a strong allergic reaction, in the germline similar arthropods can appear between the cross-reaction allergy. Adults have been many times over the years due to bites, will gradually occur “tolerance reaction”, and then again after being bitten can only produce a transient skin erythema, pain and itching and do not start the air masses,. Foreign research found that bone marrow transplant patients can occur after transplantation of papular Zunzheng measles passive transfer phenomenon, that is, the recipient produced the same papular Zunzheng measles symptoms with the donor, but the patient did not have this disease before the transplantation, the treatment of this disease, symptomatic treatment (including anti-allergic internal, external anti-itching, traditional Chinese medicine to clear the heat and dampness to relieve itching, such as bacterial infections need to be antimicrobial), the skin rash quickly subside, but very easy to recur. Prevention is very important, emphasizing the living environment of disinfection and insecticide treatment is the key to control recurrence. A variety of commercially available insecticides containing pyrethrum vinegar can be used to treat the environment, while some Chinese medicine insect repellent capsules may have a certain preventive effect; Ningbo’s old tradition of “drying out the mold” after the plum season also has a certain effect. Suspected of parasitic arthropods in the pet’s fur should be cleaned and insecticidal treatment of pets, if necessary, can be sent to the veterinary hospital.