Primary lung cancer with intrapulmonary metastasis may be localized metastasis or extensive metastasis. Surgical treatment, local radiotherapy, systemic treatment, etc. can be chosen in the light of the patient’s physical condition as well as the professional assessment by oncologists and so on. If the primary lung cancer intrapulmonary metastases are distributed in the same lung lobe, they are localized metastases and can be treated by surgery. If the patient cannot be operated or the body does not tolerate surgery, local radiotherapy can be used, or systemic treatment, such as systemic chemotherapy, targeted therapy, immunotherapy, etc. can be considered. If the primary lung cancer develops extensive metastasis in the lung, comprehensive treatment mainly based on systemic therapy should be considered. If primary lung cancer develops intrapulmonary metastasis, it is recommended to cooperate with professional oncologists to analyze and evaluate the condition as soon as possible, formulate reasonable and effective treatment plan, and control the development of the condition as soon as possible to avoid deterioration of the condition.