The treatment of pancreatic hypertrophy can be divided into surgical treatment and non-surgical treatment, and the non-surgical treatment mainly includes drug treatment and preventive treatment. For hypertrophy caused by inflammatory diseases, antibiotics can be used for anti-infective treatment, such as ustekin, gabexate mesylate, piperacillin sulbactam, etc. For pancreatic hypertrophy caused by improper diet, it is necessary to limit the intake of fat, cholesterol, sugar and other substances in the daily diet, so as not to aggravate the development of the disease. For patients with severe pancreatic hypertrophy, surgery is needed to treat the symptoms in a timely manner. Because severe pancreatic hypertrophy will cause pathological necrosis of pancreatic tissues, and in severe cases, it will lead to the occurrence of multiple organ failure, and the specific types of surgeries include juguloplasty, total pancreatectomy, and so on.