According to the data, the incidence of serious adverse drug reactions is about 6.7%, and the lethality is about 0.32%, which is quite high. So the harm caused by adverse drug reactions has been widely concerned. The harm of adverse drug reactions is mainly reflected in two aspects: First, it is the harm to the body. Adverse drug reactions generally occur in the user’s own, and in rare cases can accumulate to the next generation. For every patient who uses drugs, as long as the use of drugs may occur adverse drug reactions. Adverse drug reactions may occur in one organ or system of the body, or they may accumulate in all systems of the body and cause different degrees of damage to the body. Adverse reactions in patients may also induce new diseases, or aggravate the patient’s condition, prolong the patient’s recovery period, or even lead to disability or death in severe cases. Second, adverse reactions can also bring harm to society. Common adverse drug reactions are recurrent and prevalent, and it is social in terms of the incidence of adverse reactions. Because of the adverse reactions caused each country each year to put out a considerable amount of financial and human resources. For example, in the 1960s, it was because pregnant women had adverse reactions to drugs, and more than 10,000 deformed children were born, which was undoubtedly a devastating blow to their families. Their birth, aging, illness and death were also an extremely heavy burden on society. This event was the largest and most tragic drug disaster of the 20th century worldwide. It sounded the alarm that drug safety must be taken seriously.