Sore knee joints after drinking may be due to synovitis, gout, osteonecrosis of the femoral head, and other diseases such as osteoarthritis. 1. Synovitis: synovitis is caused by infection, trauma, immune factors and so on. Patients will show swelling, pain and fever in the knee joint. And patients drink alcohol or aggravate the inflammatory response of the body, so the symptoms of knee joint soreness will become worse after drinking alcohol. 2. Gout: the cause of gout is not yet clear, it is considered to be caused by heredity, excessive production of uric acid, etc., and the common triggering factors include the intake of purine-rich foods, drinking alcohol, etc.. Patients will have swollen and painful joints, elevated skin temperature and other manifestations, so gout patients may have symptoms of knee pain after drinking alcohol. 3. Necrosis of the femoral head: Necrosis of the femoral head may be caused by long-term heavy drinking and fracture of the femoral neck. Patients will have pain in the groin area, as well as radiating pain in the knee joints and the hip on the same side, so patients will have knee joints soreness after drinking alcohol. 4. Other: patients’ joint pain after drinking alcohol may also be caused by osteoarthritis, rheumatoid arthritis and other factors. It is recommended that patients who have knee joint pain after drinking alcohol should seek medical treatment in time, and the doctor will treat them according to the cause of the disease.