The depression on both sides of the tongue is generally considered to be induced by oral ulcers, lingual inflammation and lack of micronutrients. 1. Oral ulcers: oral ulcers can lead to localized ulcerative damage to the mucous membranes in the mouth, and the more common clinical symptom is that the ulcerated surface will be depressed, which will also cause redness, swelling and pain. 2. Tongue inflammation: Tongue inflammation belongs to a kind of chronic and non-specific inflammation of the tongue, which can cause tongue depression, tongue color change and burning symptoms. 3. Lack of micronutrients: Lack of micronutrients such as calcium, iron and zinc can also cause tongue depression. There may be other reasons for the depression on both sides of the tongue, so it is recommended to go to a regular hospital for further examination and treatment under the guidance of a specialist after the cause is clarified.