Lupus nephritis type IV is more serious, if not actively treated, most patients will gradually progress to uremia.
Lupus nephritis type IV is one of the pathologic types, namely diffuse lupus nephritis, most of the glomerular involvement of patients, which can be manifested as hyperplasia or sclerosis, and it is a more serious type of lupus nephritis, and if it is not treated aggressively, the renal function of the patients will gradually decline, which may eventually lead to uremia.
The specific severity is related to the patient’s clinical manifestations, serologic results and the degree of pathological activity.
If patients are mainly active lesions, they need induction and maintenance treatment with immunosuppressants (such as cyclophosphamide), as well as symptomatic supportive treatment such as lowering blood pressure and lipid, and correcting anemia.
Patients with lupus nephritis must actively go to regular hospitals and follow the doctor’s instructions for standardized treatment to avoid delays.