Treatment of comminuted wrist fracture generally includes general treatment, reduction and fixation, medication, surgery and so on. 1. General treatment: first of all, rest for comminuted wrist fracture, reduce wrist movement, brake to avoid re-injury. 2. Repositioning and fixation: comminuted fracture with displacement needs to be firstly manipulated and repositioned, plus cast external fixation or external fixation with support. 3. Medication: If the pain is severe, you can take analgesic and anti-inflammatory medication such as ibuprofen according to the doctor’s instructions. 4. Surgery: If the manipulation is unsuccessful and the fracture has spread to the joint surface, or even the fracture is unstable, then the patient needs to undergo surgical incision and internal fixation to restore the functional position of the joint. After the surgery, the patient should carry out gradual functional exercise as soon as possible under the guidance of the rehabilitator, so as to prevent joint stiffness in the later stage. Wrist comminuted fracture should be timely to regular hospitals, under the guidance of specialists according to the specific conditions of the appropriate treatment, the above drugs are recommended to use under the guidance of a doctor, should be avoided blindly self-medication.