Generally speaking, the reasons for the absence of follicles may be the decline of ovarian function, ovulation disorders, no sinus follicles and so on. 1. Ovarian dysfunction: excessive dieting and excessive exercise may cause endocrine hormone imbalance, resulting in ovarian dysfunction, leading to the absence of follicles. 2. Ovulation disorders: if the patient has endocrine diseases, such as polycystic ovary syndrome, prolactinemia, etc. may cause ovulation disorders, resulting in the absence of follicles. 3. No sinus follicles: if the patient has premature ovarian failure, ovarian function decline, there will be a bilateral ovary is substantial performance, that is, no sinus follicles, examination suggests that there is no follicle. Patients with no follicles should be further examined to clarify the cause of the disease and treat the symptoms.