The 24-hour quantification of urine protein is to keep all the urine for 24 hours and measure the total amount of urine protein in it. The normal 24-hour urine protein quantification is below 150mg. If it is affected by some pathological factors, such as chronic nephritis, lupus nephritis, hepatitis B virus-associated nephritis, etc., the filtration membrane of the glomerulus is damaged. If the 24-hour urine protein quantification is very high, for example, more than 3.5g, it means that the glomerular membrane is seriously damaged. At this time, it is necessary to actively give intervention, otherwise it will easily develop into renal failure. There are two main types of drugs to reduce urine protein: 1) Benadryl, valsartan capsules and xanthan capsules, which are more moderate drugs; 2) hormones and immunosuppressive drugs, such as prednisone, methylprednisolone and cyclophosphamide, etc.